Charles Leclerc claimed his first win in almost two years for Ferrari, with George Russell second and Lewis Hamilton completing the podium.
Clark called last year’s incident at Oakmont the “lowest point” of his career.
Gregor Townsend’s side have now won four of their six Tests this calendar year.
England have struggled against their Ashes rivals on several occasions.
Joseph O’Brien-trained colt made it four in a row in the Queen’s Vase.